肿瘤

Sino Biological provides a comprehensive set of reagents for studying wide broad areas of cancer research, including angiogenesis, apoptosis, cancer biomarkers, cancer stem cells, cell adhesion, signal transduction, etc.

肿瘤相关产品索引

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粘附分子	细胞周期
血管生成	G蛋白信号通路
细胞凋亡	生长因子及其受体
肿瘤生物标志物	NFkB信号通路
肿瘤干细胞	p53信号通路
癌症治疗靶点

肿瘤背景综述

Cancer is a class of diseases in which abnormal cells divide without control and are able to invade other tissues. Cancer cells can spread to other parts of the body through the blood and lymph systems. Normally, cell proliferation is under tight control through many mechanisms. For example, DNA damage and repair mechanisms exist in order to decrease the likelihood of genetic mutation and cell transformation. Apoptosis is needed to destroy cells that represent a threat to the integrity of the organism. In addition, the immune system is ready to recognize and destroy cancerous cells. However these error-correction methods often fail in small ways, especially in environments that make errors more likely to arise and propagate. Accumulating disruptions in these control mechanisms lead to progressive error accumulation until unregulated proliferation and cancer forming.