溶酶体酶

Sino biological offers a comprehensive set of tools for research on lysosomal enzymes.

These high-quality reagents include:

溶酶体酶产品

糖苷酶

溶酶体蛋白酶

硫酸酯酶

其它溶酶体蛋白

溶酶体酶背景综述

Lysosomes are membrane-bounded organelles which act as the "garbage disposal" of the cell. Lysosomes are found in all eukaryotic cells, but are most numerous in disease-fighting cells, such as leukocytes. Lysosomes digest foreign macromolecules and engulfed viruses and bacteria presenting in phagosomes. Lysosomes also break down cell components that are no longer needed. While lysosomes digest some materials in this process, it is actually accomplished through programmed cell death, called apoptosis. Lysosomes break down cellular waste products, fats, carbohydrates, proteins, and other macromolecules into simple compounds, which are then returned to the cytoplasm as new cell-building materials. To accomplish the tasks associated with digestion, the lysosomes use some 40 different types of lysosomal enzymes, such as glycosidases, protease, acid phosphatases, sulfatases and lipases. Lysosomal enzymes are synthesized in the endoplasmic reticulum and modified in the Golgi apparatus. Lysosomal enzymes are tagged for lysosomes by the addition of mannose-6-phosphate label. A deficiency of any one of these lysosomal enzymes will lead to lysosomal storage diseases, such as Tay-Sachs disease and Pompe's disease. Lysosomal enzymes are also known to be involved in cancer processes.

溶酶体酶参考文献